Zoey Woodbine (played by Alicia Witt) from Cybill
(not the most flattering picture of her, but the only one I could find of her in character)
I admit I haven't seen the show in years, but I do remember liking Zoey a lot. Maybe it was because I was a teenager myself at the time.
And will you look at that, an actual person this time, not a drawn or animated one. I'm still pissed at how suddenly the show ended, especially since it's one of the few female centric comedy shows.